Structure of PDB 7dii Chain B

Receptor sequence
>7diiB (length=491) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLV
GIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVV
AIYYVYIESWTLGFAIKFLVGLVPEPPPTDPDSILRPFKEFLYSYIGVPK
GDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILA
VFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLS
LGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFF
GVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSS
IAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFW
AGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYIT
PAFLAVLLVVWAREHWTVWITRFYIIGLFLFLTFLVFLAER
3D structure
PDB7dii Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
ChainB
Resolution2.403 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LEU B A22 G24 L25 G26 F253 T254 S256 F259 A18 G20 L21 G22 F247 T248 S250 F253
BS02 NA B A22 V23 N27 T254 N286 A18 V19 N23 T248 N280
BS03 NA B G20 V23 G24 A351 T354 S355 G16 V19 G20 A345 T348 S349
Gene Ontology
Biological Process
GO:0035725 sodium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7dii, PDBe:7dii, PDBj:7dii
PDBsum7dii
PubMed33811858
UniProtO67854

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