Structure of PDB 7dcj Chain B

Receptor sequence
>7dcjB (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
GHHHHHHVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVL
PKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPDTEFQHPCFLRGQEQ
LLENIKRKVT
3D structure
PDB7dcj Structures of heat shock factor trimers bound to DNA.
ChainB
Resolution2.004 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B G8 H9 H14 F18 K62 H63 N65 S68 R71 Q72 Y76 R117 G1 H2 H7 F11 K55 H56 N58 S61 R64 Q65 Y69 R107
BS02 dna B G8 H10 K62 R71 N74 R79 K80 G1 H3 K55 R64 N67 R72 K73
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7dcj, PDBe:7dcj, PDBj:7dcj
PDBsum7dcj
PubMed34458700
UniProtQ00613|HSF1_HUMAN Heat shock factor protein 1 (Gene Name=HSF1)

[Back to BioLiP]