Structure of PDB 7dc8 Chain B

Receptor sequence

>7dc8B (length=209) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGDLVKPGGGLRLSCAASGFTFSSYTMNWVRQAPGKGLEWVSS
ISSQSYHIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARYG
KLYSLNWVFDYWGQGTLVTVSSASTKGPSVFPLAPALGCLVKDYFPEPVT
VSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSQTYICNVNHKPSN
TKVDKKVEP

3D structure

PDB

7dc8 Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment.

Chain

Resolution

2.757 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	B	T33 S52 S52A Q53 H56 Y95 G96 L98 L100A N100B W100C	T33 S52 S53 Q54 H57 Y99 G100 L102 L105 N106 W107

External links

PDB	RCSB:7dc8, PDBe:7dc8, PDBj:7dc8
PDBsum	7dc8
PubMed	33357423

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