Structure of PDB 7day Chain B

Receptor sequence
>7dayB (length=220) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
QPKPILYYDERSPPVRSCLMLIKLLDIDVELRFVNLFKGEQFQKDFLALN
PQHSVPTLVHGDLVLTDSHAILIHLAEKFDEGGSLWPQEHAERMKVLNLL
LFECSFLFRRDSDFMSAIVRQGFANVDVAHHERKLTEAYIIMERYLENSD
FMAGPQLTLADLSIVTTLSTVNLMFPLSQFPRLRRWFTAMQQLDAYEANC
SGLEKLRQTMESVGSFQFPS
3D structure
PDB7day Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo
ChainB
Resolution1.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 H1X B E79 W88 R95 E77 W86 R93
BS02 H1X B P15 L38 F110 S114 L208 P13 L36 F108 S112 L206
BS03 GSH B S14 P16 L38 Q43 H55 S56 V57 D69 S70 H71 F110 S12 P14 L36 Q41 H53 S54 V55 D67 S68 H69 F108
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004364 glutathione transferase activity
GO:0004769 steroid delta-isomerase activity
GO:0016740 transferase activity
Biological Process
GO:0006694 steroid biosynthetic process
GO:0006749 glutathione metabolic process
GO:0009636 response to toxic substance
GO:0042632 cholesterol homeostasis
GO:0045456 ecdysteroid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:7day, PDBe:7day, PDBj:7day
PDBsum7day
PubMed
UniProtQ7JYX0|GSTEE_DROME Glutathione S-transferase E14 (Gene Name=GstE14)

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