Structure of PDB 7das Chain B

Receptor sequence
>7dasB (length=671) Species: 10090 (Mus musculus) [Search protein sequence]
YFQSQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFT
RYSQLAILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFC
TNLTELDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQLEN
LQELLLAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTIGK
LFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSGLK
WTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLS
NLRYLSLKRAFTKQSASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTF
TGLVSLKYLSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANG
TFSWLGQLRILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLSTSS
FALVPSLQRLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINEDL
LEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHILNLESNGLD
EIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSV
EKDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHY
LCNTPHHYYGFPLKLFDTSSC
3D structure
PDB7das Endosomal lncRNA Rmrp is required for TLR3 innate sensing by engaging TLR3 dimerization
ChainB
Resolution3.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B H40 K42 H61 Q63 F85 N86 S87 S89 H109 E111 R490 N516 N518 A520 H540 N542 G574 H17 K19 H38 Q40 F62 N63 S64 S66 H86 E88 R464 N490 N492 A494 H514 N516 G548
External links
PDB RCSB:7das, PDBe:7das, PDBj:7das
PDBsum7das
PubMed
UniProtQ99MB1|TLR3_MOUSE Toll-like receptor 3 (Gene Name=Tlr3)

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