Structure of PDB 7d9g Chain B

Receptor sequence

>7d9gB (length=588) Species: 208964 (Pseudomonas aeruginosa PAO1)

GRYYPPALTGLRGSHPGAFEVAHQMGWEKKTFDVDHLPIEEEYDLVVVGG
GISGLAAAWFYRERHPAARILVIENHDDFGGHAKRNEFQAGGRTILGYGG
SESLQSPNALYSEDAKHLLKRLGVELKRFETAFDTDFYPGLGLSRAVFFD
KASFGVDKLVSGDPTPMVADEVPRDRLNARSWRAFIGDFPLSREDREALI
ALYESPRDYLAGKSVEEKETYLAKTSYRDYLLKNVGLSETSVKYFQGRSN
DFSALGADALPAADAYAAGFPGFDALGLPQPSEEAQAEMDEPYIYHFPDG
NASLARLMVRDLIPAVAPGRGMEDIVMARFDYSKLDLAGHPVRLRLNSTA
VSVRNRAGGVDVGYSRAGRLHRVRGKHCVMACYNMMVPYLLRDLSEEQAH
ALSQNVKFPLVYTKVLLRNWQAWKTLGIHEIYAPTLPYSRIKLDFPVDLG
SYRHPRDPRQPIGVHMVYVPTTPNAGMDARTQARVGRSKLYAMSFEQLEK
DIRDQLQAMLGPAGFDHRRDITGITVNRWSHGYSYFMNTLYDDEAESEAL
MELARSKVGNVAIANSDAAWDAYAHAAIDQAVRAVREL

3D structure

• PDB: 7d9g Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold.
• Chain: B
• Resolution: 2.4 Å

Enzymatic activity

• Enzyme Commision number: 1.5.99.6: spermidine dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	B	V79 G82 S84 E105 N106 H107 G112 H113 G131 S132 E133 S134 T380 A381 C413 Y414 M417 Y443 G563 Y564 N596 S597 A603 Y604 A605	V48 G51 S53 E74 N75 H76 G81 H82 G100 S101 E102 S103 T349 A350 C382 Y383 M386 Y412 G532 Y533 N565 S566 A572 Y573 A574
BS02	HEM	B	S45 F50 A53 H54 W58 N106 Y414 M416 Y420 R518 S519 Y522 R559 S561 H562	S14 F19 A22 H23 W27 N75 Y383 M385 Y389 R487 S488 Y491 R528 S530 H531

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:7d9g, PDBe:7d9g, PDBj:7d9g
• PDBsum: 7d9g
• PubMed: 34741591
• UniProt: Q9HXS8