Structure of PDB 7d9f Chain B

Receptor sequence

>7d9fB (length=587) Species: 208964 (Pseudomonas aeruginosa PAO1)

RYYPPALTGLRGSHPGAFEVAHQMGWEKKTFDVDHLPIEEEYDLVVVGGG
ISGLAAAWFYRERHPAARILVIENHDDFGGHAKRNEFQAGGRTILGYGGS
ESLQSPNALYSEDAKHLLKRLGVELKRFETAFDTDFYPGLGLSRAVFFDK
ASFGVDKLVSGDPTPMVADEVPRDRLNARSWRAFIGDFPLSREDREALIA
LYESPRDYLAGKSVEEKETYLAKTSYRDYLLKNVGLSETSVKYFQGRSND
FSALGADALPAADAYAAGFPGFDALGLPQPSEEAQAEMDEPYIYHFPDGN
ASLARLMVRDLIPAVAPGRGMEDIVMARFDYSKLDLAGHPVRLRLNSTAV
SVRNRAGGVDVGYSRAGRLHRVRGKHCVMACYNMMVPYLLRDLSEEQAHA
LSQNVKFPLVYTKVLLRNWQAWKTLGIHEIYAPTLPYSRIKLDFPVDLGS
YRHPRDPRQPIGVHMVYVPTTPNAGMDARTQARVGRSKLYAMSFEQLEKD
IRDQLQAMLGPAGFDHRRDITGITVNRWSHGYSYFMNTLYDDEAESEALM
ELARSKVGNVAIANSDAAWDAYAHAAIDQAVRAVREL

3D structure

• PDB: 7d9f Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold.
• Chain: B
• Resolution: 1.85 Å

Enzymatic activity

• Enzyme Commision number: 1.5.99.6: spermidine dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	B	V79 G80 G82 S84 E105 N106 H107 G112 H113 G131 S132 E133 S134 A381 C413 Y414 M417 Y443 G563 Y564 N596 S597 A603 Y604 A605 A608	V47 G48 G50 S52 E73 N74 H75 G80 H81 G99 S100 E101 S102 A349 C381 Y382 M385 Y411 G531 Y532 N564 S565 A571 Y572 A573 A576
BS02	HEM	B	S45 F50 A53 H54 W58 H107 Y414 M416 M417 Y420 R518 S519 Y522 R559 S561 H562	S13 F18 A21 H22 W26 H75 Y382 M384 M385 Y388 R486 S487 Y490 R527 S529 H530

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:7d9f, PDBe:7d9f, PDBj:7d9f
• PDBsum: 7d9f
• PubMed: 34741591
• UniProt: Q9HXS8