Structure of PDB 7d8t Chain B

Receptor sequence
>7d8tB (length=199) Species: 9606,224324 [Search protein sequence]
SLAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTIL
KASVDYIRKLQREQQRAKELENRQKKLEHACRHLLLRIQELGIEDFLKVD
LRVAKVLSAERVEGSEKLLKLTLSLGDEERTVVAGIAKYYTPEELVGKKI
VIVANLKPRKIFGIESQGMILAASDGENLSVIVPDRDVKEGAKLSAALE
3D structure
PDB7d8t A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
ChainB
Resolution3.201 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B H316 R321 R324 N328 N349 K350 H12 R17 R20 N24 N45 K46
BS02 dna B E320 R323 E16 R19
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004825 methionine-tRNA ligase activity
GO:0005524 ATP binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006431 methionyl-tRNA aminoacylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7d8t, PDBe:7d8t, PDBj:7d8t
PDBsum7d8t
PubMed36588115
UniProtO66738;
O75030

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