Structure of PDB 7crc Chain B

Receptor sequence
>7crcB (length=1112) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
RIWKHQVFPSFHGADVRKTILSHILESFRRKGIDPFIDNNIERSKSIGHE
LKEAIKGSKIAIVLLSKNYASSSWCLDELAEIMKCRELLGQIVMTIFYEV
DPTDIKKQTGEFGKAFTKTCKGKTKEYVERWRKALEDVATIAGYHSHKWR
NEADMIEKIATDVSNMLNSFKPSRDFNGLVGMRAHMDMLEQLLRLVLDEV
RMIGIWGPPGIGKTTIARFLFNQVSDRFQLSAIMVNIKGCYPRPCFDEYS
AQLQLQNQMLSQMINHKDIMISHLGVAQERLRDKKVFLVLDEVDQLGQLD
ALAKETRWFGPGSRIIITTEDLGVLKAHGINHVYKVGYPSNDEAFQIFCM
NAFGQKQPHEGFDEIAREVMALAGELPLGLKVLGSALRGKSKPEWERTLP
RLKTSLDGKIGSIIQFSYDALCDEDKYLFLYIACLFNKESTTKVEGLLGK
FLDVRQGLHILAQKSLISIEDGNIYMHTLLEQFGRETSRKQFIHHGYTKH
QLLVGERDICEVLNDDTIDSRRFIGINLDLYKNVEELNISEKALERIHDF
QFVRINGKNHALHERLQGLIYQSPQIRSLHWKCYQNICLPSTFNSEFLVE
LDMSFSKLQKLWEGTKQLRNLKWMDLSYSSYLKELPNLSTATNLEELKLR
NCSSLVELPSSIEKLTSLQILDLHRCSSLVELPSFGNATKLEILNLENCS
SLVKLPPSINANNLQELSLTNCSRVVELPAIENATNLWKLNLLNCSSLIE
LPLSIGTATNLKHLDFRGCSSLVKLPSSIGDMTNLEVFYLSNCSNLVELP
SSIGNLRKLTLLLMRGCSKLETLPTNINLKSLHTLNLIDCSRLKSFPEIS
THIKYLRLIGTAIKEVPLSIMSWSPLAHFQISYFESLKEFPHALDIITEL
QLSKDIQEVPPWVKRMSRLRALRLNNCNNLVSLPQLPDSLAYLYADNCKS
LERLDCCFNNPEIRLYFPKCFKLNQEARDLIMHTSTRNFAMLPGTQVPAC
FNHRATSLKIKLKESPLPTTLTFKACIMLVNEEMSYDLKSMSVDIVIRDE
QNDLKVQCTPSYHQCTEIYVLTEHIYTFELEVEEVTSTELVFEFTSVNES
ICKIGECGILQR
3D structure
PDB7crc Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme.
ChainB
Resolution3.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.6: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B L259 V260 G290 G292 K293 T294 T295 I427 P457 K461 L179 V180 G210 G212 K213 T214 T215 I347 P377 K381
BS02 ATP B F91 H92 G93 I127 W154 E158 F11 H12 G13 I47 W74 E78
Gene Ontology
Biological Process
GO:0006950 response to stress
GO:0006952 defense response
GO:0007165 signal transduction

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7crc, PDBe:7crc, PDBj:7crc
PDBsum7crc
PubMed33273071
UniProtQ9ZSN5

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