Structure of PDB 7cq2 Chain B

Receptor sequence
>7cq2B (length=297) Species: 307796 (Saccharomyces cerevisiae YJM789) [Search protein sequence]
KIQQHQFPDFYCCYLLQSINKRQSFYVGSTPNPVRRLRQHNGKLAVGGAY
RTKRDGSRPWEMIMIVRGFPSKIAALQFEHAWQHGYQTHYIAEKDRVVKH
KAGGRTLHHKVALMKLLLKHEFFQRMNLIVEVFNIKAWEVWKQDKFFIER
DRFPINIQINENALEEPKEKTVDVLMDHSDENLKVVEAVYTKVIENERNI
FETFEKKLTTGVVRCEICEKEIDYTSENLKPFVALCNNKDCGCVNHLKCL
HRYFLDDEQLIVGRRNLIPRGGKCPKCDMFCDWTTLVKFSTRMKLAH
3D structure
PDB7cq2 Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C218 H251 C254 C215 H246 C249
BS02 ZN B C241 C246 C279 C282 C236 C241 C274 C277
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:1902681 regulation of replication fork arrest at rDNA repeats
GO:2000001 regulation of DNA damage checkpoint
Cellular Component
GO:0000228 nuclear chromosome
GO:0005634 nucleus
GO:0033557 Slx1-Slx4 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cq2, PDBe:7cq2, PDBj:7cq2
PDBsum7cq2
PubMed34181713
UniProtP38324|SLX1_YEAST Structure-specific endonuclease subunit SLX1 (Gene Name=SLX1)

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