Structure of PDB 7cpd Chain B

Receptor sequence
>7cpdB (length=417) Species: 9913 (Bos taurus) [Search protein sequence]
REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYY
NEKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGH
YTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKI
REEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNE
ALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAV
NMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYL
TVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGL
KMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEA
ESNMNDLVSEYQQYQDA
3D structure
PDB7cpd Crystal structure of T2R-TTL-(+)-6-Br-JP18 complex
ChainB
Resolution2.506 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G9U B C241 L242 L248 A250 N258 N350 K352 C234 L235 L241 A243 N251 N337 K339
BS02 CA B E110 E113 E103 E106
BS03 GDP B Q11 C12 S140 G143 G144 T145 D179 E183 N206 Y224 N228 Q10 C11 S133 G136 G137 T138 D172 E176 N199 Y217 N221
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
GO:0007399 nervous system development
GO:1902669 positive regulation of axon guidance
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cpd, PDBe:7cpd, PDBj:7cpd
PDBsum7cpd
PubMed
UniProtQ6B856|TBB2B_BOVIN Tubulin beta-2B chain (Gene Name=TUBB2B)

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