Structure of PDB 7coj Chain B

Receptor sequence
>7cojB (length=209) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
SDKFSAALAKNKEWAAKCSQEHPELLPTLAVGQHPEILWIGCSDSRCPET
TILGLLPGDVFTHRNIANVIHPADLSSGAVIEFAVRHLRVKHVVICGHTK
CGGVAAALGNKGLGILDPWLIPLRQLREQHLAELQSLSRDEAVVRLAELN
VKEGLKALTQKSVVLEAMQERGLQVHGLIYDVGSGFLRQLDAAEPEEALK
ARLTSFKTD
3D structure
PDB7coj Crystal Structure of beta-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus .
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AZM B F138 F160 F61 F83
BS02 ZN B C119 H175 C178 C42 H98 C101
BS03 AZM B C119 D121 H175 G179 G180 L193 C42 D44 H98 G102 G103 L116
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization
GO:0034599 cellular response to oxidative stress
GO:0071244 cellular response to carbon dioxide
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7coj, PDBe:7coj, PDBj:7coj
PDBsum7coj
PubMed32975213
UniProtQ4WQ18

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