Structure of PDB 7cme Chain B

Receptor sequence
>7cmeB (length=214) Species: 9606 (Homo sapiens) [Search protein sequence]
MDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEG
VFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVT
DQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYS
IHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGD
GSTTTAVAVVEILD
3D structure
PDB7cme Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
ChainB
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G60 B S201 T202 S202 T203
BS02 CA B N102 H104 D134 D136 N143 D195 N103 H105 D135 D137 N144 D196
BS03 CA B E11 E69 D100 Q101 D103 D136 E12 E70 D101 Q102 D104 D137
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cme, PDBe:7cme, PDBj:7cme
PDBsum7cme
PubMed
UniProtP22223|CADH3_HUMAN Cadherin-3 (Gene Name=CDH3)

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