Structure of PDB 7cec Chain B

Receptor sequence
>7cecB (length=427) Species: 9606 (Homo sapiens) [Search protein sequence]
NRCLKANAKSCGECIQAGPNCGWCTNSTFLTSARCDDLEALKKKGCPPDD
IENPRGSKDIKKNKNVTNLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKR
AEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSF
VEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVG
KQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGD
GKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAV
TEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENG
KLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPK
KDSDSFKIRPLGFTEEVEVILQYICEC
3D structure
PDB7cec Structural mechanism of laminin recognition by integrin.
ChainB
Resolution3.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B E169 N224 D226 P228 E229 E152 N207 D209 P211 E212
BS02 MN B S132 S134 E229 S115 S117 E212
BS03 MN B S134 D137 D138 D259 S117 D120 D121 D242
External links
PDB RCSB:7cec, PDBe:7cec, PDBj:7cec
PDBsum7cec
PubMed34188035
UniProtP05556|ITB1_HUMAN Integrin beta-1 (Gene Name=ITGB1)

[Back to BioLiP]