Structure of PDB 7cba Chain B

Receptor sequence
>7cbaB (length=768) Species: 8656 (Naja atra) [Search protein sequence]
DICVLPTQSWSCNKLRCGEKRMANVLCSCSEDCLTKKDCCTDYKSICKRE
TSWLKDQCAQCPEGFDQSPLILFSMDGFRAEYLETWDTLMPNINKLKTCG
THAKYMRAVYPTKTFVNHYTIVTGLYAETHGIIDNNMYDVKLNQNFSLSG
SNMRNAAWWGGQPIWHTASYQGLKAATYFWPGSEVKINGSYPTIYKVYNK
STPFEARVMEVLKWLDLPKAKRPDFSTLYIEEPDTTGHKFGPVSGQVIKS
LQMADRTLGMLMEGLKQRNLHNCVNLILLADHGMEAISCNRLEYMTDYFN
TVDFFMYEGAAPRIRSKNVPKDFYTFDSEAIVKKLTCRKPKQHFKAYLAK
DLPKRLHFANNIRIDKVNLMVDRQWLAVRNKKYKYCSGGTHGYDNEFKSM
EAIFLAHGPGFKEKTEVTSFENIEVYNLMCDLLKLKPAPNNGTHGSLNHL
LKNPFYNPSPAKEQSPPLYCLFGPVPSPDVSGCKCSSITDLEAVNQRLNL
IDQAKMQSEADNLPYGRPHVLQHSKYCLLHQTKYISAYSQDILMPLWNSY
TISKSDCLRLDVRIPTVQSQTCSNYQPDLAITPGFLYPPDFSSSGPEQYD
ALITSNIVPMYKEFARLWNYFHSTLLPKYATERNGLNVISGPIFDYNYDG
HFDPYDTIDQYVNNTKIPIPTHYFVVLTSCENSTKTPLNCPPGSLKVLSF
ILPHRPDNSESCADKSPDNLWVEERMQTHTARVRDVELLTGLDFYSALKQ
PLSETLRLKTFLPIFINS
3D structure
PDB7cba Crystal structure of snake venom phosphodiesterase (PDE) from Taiwan cobra (Naja atra atra) in complex with isorhamnetin and citrate
ChainB
Resolution2.901 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B D305 H309 H462 D234 H238 H391
BS02 ZN B D147 T185 D352 H353 D76 T114 D281 H282
BS03 CA B D728 N730 D732 H734 F735 D736 D645 N647 D649 H651 F652 D653
BS04 IRH B F186 F250 W251 P252 Y269 K271 Y300 D305 T306 F115 F179 W180 P181 Y198 K200 Y229 D234 T235
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0016787 hydrolase activity
GO:0043262 ADP phosphatase activity
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity
GO:0090729 toxin activity
Biological Process
GO:0009143 nucleoside triphosphate catabolic process
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7cba, PDBe:7cba, PDBj:7cba
PDBsum7cba
PubMed
UniProtA0A2D0TC04|PDE_NAJAT Venom phosphodiesterase

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