Structure of PDB 7bee Chain B

Receptor sequence
>7beeB (length=373) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
MLSPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLG
GKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRL
YGPSSVSFAEDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGK
LPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGV
TMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKL
LTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNK
ADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDELRSPKLFYADHPFIFL
VRDTQSGSLLFIGRLVRPKGDKM
3D structure
PDB7bee Collagen's primary structure determines collagen:HSP47 complex stoichiometry.
ChainB
Resolution1.939 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B M218 R222 H238 D385 M184 R188 H204 D344
BS02 peptide B M225 V275 L381 Y383 M191 V241 L340 Y342
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005518 collagen binding
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7bee, PDBe:7bee, PDBj:7bee
PDBsum7bee
PubMed34487762
UniProtA0A8I3N7V2

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