Structure of PDB 7bbd Chain B

Receptor sequence
>7bbdB (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGK
QLEDGRTLSDYNIQKESTLHLVLRLRAAMASAARLTMMWEEVTCPICLDP
FVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANM
VNNLKEISQE
3D structure
PDB7bbd RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C92 C95 C112 C115 C94 C97 C114 C117
BS02 ZN B C107 H109 C127 C130 C109 H111 C129 C132
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:7bbd, PDBe:7bbd, PDBj:7bbd
PDBsum7bbd
PubMed33619271
UniProtP0CG47|UBB_HUMAN Polyubiquitin-B (Gene Name=UBB);
P19474|RO52_HUMAN E3 ubiquitin-protein ligase TRIM21 (Gene Name=TRIM21)

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