Structure of PDB 7bah Chain B

Receptor sequence
>7bahB (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
DKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPK
QFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGV
QTLYSKWKDFHFEKIPFDPAEM
3D structure
PDB7bah A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
ChainB
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B F853 S854 F52 S53
BS02 rna B C829 H830 F853 I875 V886 K888 C28 H29 F52 I74 V85 K87
BS03 ZN B C810 C813 C864 C869 C9 C12 C63 C68
External links
PDB RCSB:7bah, PDBe:7bah, PDBj:7bah
PDBsum7bah
PubMed
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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