Structure of PDB 7b6q Chain B

Receptor sequence
>7b6qB (length=476) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
RNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGADGRRYIPQA
IAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEP
SDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPG
SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLDME
HYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNC
HGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATL
LALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKAL
QAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTE
EPRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHE
DYQIVGNQRLDYSDRVTVARLLGVIA
3D structure
PDB7b6q Crystal structure of MurE from E.coli
ChainB
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.13: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WZD B T115 L189 S202 V203 F204 L228 Y229 I239 W249 T110 L179 S192 V193 F194 L209 Y210 I220 W230
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008765 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009058 biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7b6q, PDBe:7b6q, PDBj:7b6q
PDBsum7b6q
PubMed
UniProtP22188|MURE_ECOLI UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (Gene Name=murE)

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