Structure of PDB 7b57 Chain B

Receptor sequence
>7b57B (length=303) Species: 10090 (Mus musculus) [Search protein sequence]
TCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDH
QKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAR
EYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKL
ADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILY
ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTI
NPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAIL
AAM
3D structure
PDB7b57 Crystal structure of CaMKII-actinin complex bound to ADP
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.17: calcium/calmodulin-dependent protein kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B G20 K21 G22 V27 A40 K42 L91 V92 D156 G16 K17 G18 V23 A36 K38 L87 V88 D152
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7b57, PDBe:7b57, PDBj:7b57
PDBsum7b57
PubMed
UniProtP11798|KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II subunit alpha (Gene Name=Camk2a)

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