Structure of PDB 7b0j Chain B

Receptor sequence
>7b0jB (length=682) Species: 7955 (Danio rerio) [Search protein sequence]
RIPLRIVRAESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININCI
DPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLL
NHKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVVDSLRHS
RSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEE
LSHQCKHFAKDLLDQTRSSRELELILNFRNELARLKLAIKYRQKEFVAQP
NCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSR
YGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSNNPDRQGPKPTTVEW
MILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIV
AYVKYSGCKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGP
LQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRC
ERQNNAFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTY
NVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLP
PPFNIIPSPKSICYLITWIKVHRAAENVRLNHQYQEVLRNLVKRYVAAMI
RDAKTEEGLTEENFKELKQDISSFRYEVIGMM
3D structure
PDB7b0j Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
ChainB
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E417 Q420 N435 D438 E363 Q366 N381 D384
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005261 monoatomic cation channel activity
GO:0005262 calcium channel activity
GO:0015279 store-operated calcium channel activity
GO:0070679 inositol 1,4,5 trisphosphate binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0006812 monoatomic cation transport
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0034703 cation channel complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7b0j, PDBe:7b0j, PDBj:7b0j
PDBsum7b0j
PubMed33236980
UniProtU3N7D8

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