Structure of PDB 7aoh Chain B

Receptor sequence
>7aohB (length=1134) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence]
EMDQRLGYKFLVPDPKAGVFYRPLHFQYVSYSNFILHRLHEILTVKRPLL
SFKNNTERIMIEISNVKVTPPDYSPIIASIKGKSYDALATFTVNIFKEVM
TKEGISITKISSYEGKDSHLIKIPLLIGYGNKNPLDTAKYLVPNVIGGVF
INKQSVEKVGINLVEKITTWPKFRVVKPNSFTFSFSSVSPPNVLPTRYRH
YKISLDISQLEALNISSTKTFITVNIVLLSQYLSRVSLEFIRRSLSYDMP
PEVVYLVNAIIDSAKRITESITDFNIDTYINDLVEAEHIKQKSQLTINEF
KYEMLHNFLPHMNYTPDQLKGFYMISLLRKFLYCIFHTSRYPDRDSMVCH
RILTYGKYFETLAHDELENYIGNIRNDIMNNHKNRGTYAVNIHVLTTPGL
NHAFSSLLSGKFKKSDGSYRTHPHYSWMQNISIPRSVGFYPSVRKYHPSQ
YLYFCSSDVPERGPQVGLVSQLSVLSSITNILTSEYLDLEKKICEYIRSY
YKDDISYFETGFPITIENALVASLNPNMICDFVTDFRRRKRMGFFGNLEV
GITLVRDHMNEIRINIGAGRLVRPFLVVDNGELMMDVCPELESRLDDMTF
SDIQKEFPHVIEMVDIEQFTFSNVCESVQKFRMMSKDERKQYDLCDFPAE
FRDGYVASSLVGINHNSGPRAILGCAQAKQAISCLSSDIRNKIDNGIHLM
YPERPIVISKALETSKIAANCFGQHVTIALMSYKGINQEDGIIIKKQFIQ
RGGLDIVTAKKHQVEIPLENFNNKERDRSNAYSKLESNGLVRLNAFLESG
DAMARNISSISFDVSEKYTDMYKSRVERVQVELTDKVKVRVLTMKERRPI
LGDKFTTRTSQKGTVAYVADETELPYDENGITPDVIINSTSIFSRKTISM
LIEVILTAAYSAKPYNNKGENRPVCFPSSNETSIDTYMQFAKQCYEHSNP
KLSDEELSDKIFCEKILYDPETDKPYASKVFFGPIYYLRLRHLTQDKATV
RCRGKKTKLIRQANEGRKRGGGIKFGEMERDCLIAHGAANTITEVLKDSE
EDYQDVYVCENCGDIAAQIKGINTCLRCSKLNLSPLLTKIDTTHVSKVFL
TQMNARGVKVKLDFERRPPSFYKPLDKVDLKPSF
3D structure
PDB7aoh Structural basis of the complete poxvirus transcription initiation process.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B R478 Q481 Q696 K890 H1020 T1035 K1036 R462 Q465 Q680 K862 H992 T1007 K1008
BS02 dna B Q161 V163 N711 K777 R1045 K1046 K1052 M1056 Q154 V156 N695 K761 R1017 K1018 K1024 M1028
BS03 ZN B C1087 C1090 C1103 C1106 C1059 C1062 C1075 C1078
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006360 transcription by RNA polymerase I
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aoh, PDBe:7aoh, PDBj:7aoh
PDBsum7aoh
PubMed34556871
UniProtQ49PH2

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