Structure of PDB 7amv Chain B

Receptor sequence
>7amvB (length=1126) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence]
EMDQRLGYKFLVPDPKAGVFYRPLHFQYVSYSNFILHRLHEILTVKRPLL
SFKNNTERIMIEISNVKVTPPDYSPIIASIKGKSYDALATFTVNIFKEVM
TKEGISITKISSYEGKDSHLIKIPLLIGYGNKNPLDTAKYLVPNVIGGVF
INKQSVEKVGINLVEKITTWPKFRVVKPNSFTFSFSSVSPPNVLPTRYRH
YKISLDISQLEALNISSTKTFITVNIVLLSQYLSRVSLEFIRRSLSYDMP
PEVVYLVNAIIDSAKRITESITDFNIDTYINDLVEAEHIKQKSQLTINEF
KYEMLHNFLPHMNYTPDQLKGFYMISLLRKFLYCIFHTSRYPDRDSMVCH
RILTYGKYFETLAHDELENYIGNIRNDIMNNHKNRGTYAVNIHVLTTPGL
NHAFSSLLSGKFKKSDGSYRTHPHYSWMQNISIPRSVGFYPSVRKYHPSQ
YLYFCSSDVPERGPQVGLVSQLSVLSSITNILTSEYLDLEKKICEYIRSY
YKDDISYFETGFPITIENALVASLNPNMICDFVTDFRRRKRMGFFGNLEV
GITLVRDHMNEIRINIGAGRLVRPFLVVDNGELMMDVCPELESRLDDMTF
SDIQKEFPHVIEMVDIEQFTFSNVCESVQKFRMMSKDERKQYDLCDFPAE
FRDGYVASSLVGINHNSGPRAILGCAQAKQAISCLSSDIRNKIDNGIHLM
YPERPIVISKALETSKIAANCFGQHVTIALMSYKGINQEDGIIIKKQFIQ
RGGLDIVTAKKHQVEIPLENFNNAYSKLESNGLVRLNAFLESGDAMARNI
SSSFDVSEKYTDMYKSRVERVQVELTDKVKVRVLTMKERRPILGDKFTTR
TSQKGTVAYVADETELPYDENGITPDVIINSTSIFSRKTISMLIEVILTA
AYSAKPYNNKGENRPVCFPSSNETSIDTYMQFAKQCYEHSNPKLSDEELS
DKIFCEKILYDPETDKPYASKVFFGPIYYLRLRHLTQDKATVRCRGKKTK
LIRQANEGRKRGGGIKFGEMERDCLIAHGAANTITEVLKDSEEDYQDVYV
CENCGDIAAQIKGINTCLRCSKLNLSPLLTKIDTTHVSKVFLTQMNARGV
KVKLDFERRPPSFYKPLDKVDLKPSF
3D structure
PDB7amv Structural basis of the complete poxvirus transcription initiation process.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K60 G393 K53 G386
BS02 ZN B C1087 C1103 C1106 C1051 C1067 C1070
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006360 transcription by RNA polymerase I
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7amv, PDBe:7amv, PDBj:7amv
PDBsum7amv
PubMed34556871
UniProtQ49PH2

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