Structure of PDB 7ama Chain B

Receptor sequence
>7amaB (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
PRTVMVNLNIHSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINA
DGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPI
3D structure
PDB7ama Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein-Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases.
ChainB
Resolution2.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RMK B P63 I66 W67 E95 I96 L97 P34 I37 W38 E66 I67 L68
Gene Ontology
Molecular Function
GO:0005125 cytokine activity
Biological Process
GO:0006954 inflammatory response
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:7ama, PDBe:7ama, PDBj:7ama
PDBsum7ama
PubMed35767390
UniProtQ16552|IL17_HUMAN Interleukin-17A (Gene Name=IL17A)

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