Structure of PDB 7aic Chain B

Receptor sequence
>7aicB (length=663) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
RQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAE
LLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGV
ENAPRGLSAAGALLQYAKCTQRTTLPHIRSITMEREQDSIIMDAATRRNL
EITQNLAGGAENTLASVLDSTVTPMGSRMLKRWLHMPVRDTRVLLERQQT
IGALQDFTAGLQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPE
LRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIAS
GYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQI
SRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQL
YEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTSPTFIDKPG
IRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQT
ALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAFMVEMTETANILHNATEY
SLVLMDEIGRGTSTYDGLSLAWAVAENLANKIKALTLFATHYFELTQLPE
KMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIK
RARQKLRELESIS
3D structure
PDB7aic The selection process of licensing a DNA mismatch for repair.
ChainB
Resolution5.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B T359 R420 T232 R293
BS02 dna B R363 R367 T414 R236 R240 T287
BS03 ANP B F670 M671 F533 M534
BS04 ANP B V588 L592 E594 M617 G619 K620 S621 D693 H760 V461 L465 E467 M490 G492 K493 S494 D556 H623
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008301 DNA binding, bending
GO:0016887 ATP hydrolysis activity
GO:0030983 mismatched DNA binding
GO:0032136 adenine/cytosine mispair binding
GO:0042802 identical protein binding
GO:0043531 ADP binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0000018 regulation of DNA recombination
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0006974 DNA damage response
Cellular Component
GO:0005829 cytosol
GO:0032300 mismatch repair complex
GO:1990710 MutS complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aic, PDBe:7aic, PDBj:7aic
PDBsum7aic
PubMed33820992
UniProtP23909|MUTS_ECOLI DNA mismatch repair protein MutS (Gene Name=mutS)

[Back to BioLiP]