Structure of PDB 7ae6 Chain B

Receptor sequence
>7ae6B (length=143) Species: 1532906 (Aphanizomenon flos-aquae 2012/KM1/D3) [Search protein sequence]
IEPVIIETRLELIGRYLDHLKKFENISLDDYLSSFEQQLITERLLQLITQ
AAIDINDHILSKLKSKSYTNFEAFIELGKYQILTPELAKQIAPSSGLANR
LVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEEEND
3D structure
PDB7ae6 HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.27.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AMP B F75 P97 N103 Y109 F71 P93 N99 Y105
BS02 AMP B R104 D113 Q116 R100 D109 Q112
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004519 endonuclease activity
GO:0004540 RNA nuclease activity
Cellular Component
GO:0110001 toxin-antitoxin complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:7ae6, PDBe:7ae6, PDBj:7ae6
PDBsum7ae6
PubMed33290744
UniProtA0A0B0QJR1|HEPT_APHF2 tRNA nuclease HepT (Gene Name=hepT)

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