Structure of PDB 6zzp Chain B

Receptor sequence
>6zzpB (length=254) Species: 334543 (Psychrobacter arcticus) [Search protein sequence]
ATQLQQDLTGKVALVTGAASGIGRDIAETYAKAGAAVGIADINLEAAQKT
VDAIEAAGGRALAIAMDVTSEAAVNDGVQRLVDTFGGIDILVSNAGIQII
DPIHKMAFEDWKKMLAIHLDGAFLTTKAAIQHMYKDDKGGTVIYMGSVHS
HEASLFKAPYVTAKHGLLGLCRVLAKEGAVHNVRSHVICPGFVKTPLVEK
QIPQVVNDIMLVNTVDKEFTTVDDIAQLALFLAAFPTNVFTGQSIVASHG
WFMN
3D structure
PDB6zzp Dissecting the Mechanism of ( R )-3-Hydroxybutyrate Dehydrogenase by Kinetic Isotope Effects, Protein Crystallography, and Computational Chemistry.
ChainB
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.30: 3-hydroxybutyrate dehydrogenase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD B G18 S21 G22 I23 D42 I43 M67 D68 V69 N95 A96 M146 Y161 K165 P191 F193 V194 T196 L198 V199 G17 S20 G21 I22 D41 I42 M66 D67 V68 N94 A95 M145 Y160 K164 P190 F192 V193 T195 L197 V198
BS02 QT8 B Q99 S148 H150 K158 Y161 F193 Q202 Q98 S147 H149 K157 Y160 F192 Q201
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003858 3-hydroxybutyrate dehydrogenase activity
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:6zzp, PDBe:6zzp, PDBj:6zzp
PDBsum6zzp
PubMed33391858
UniProtQ4FRT2

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