Structure of PDB 6zpl Chain B

Receptor sequence
>6zplB (length=530) Species: 9606 (Homo sapiens) [Search protein sequence]
IEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPAFFM
ELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYY
FFSSMTHVLPWAYCNNPWNTHDCAGVLDHSLQRTSPSEEYWRLYVLKLSD
DIGNFGEVRLPLLGCLGVAWLVVFLCLIRGVVYFTATFPYVVLTILFVRG
VTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQAFYSLGCAWGGLITMAS
YNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVAD
HGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAI
VDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASF
SLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAII
FFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLAR
TDGDTLLQRLKNATKPSRDWGPALLEHRTG
3D structure
PDB6zpl Structural insights into the inhibition of glycine reuptake.
ChainB
Resolution3.945 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QET B Y116 V118 G119 G121 S371 W376 G378 M382 I399 T472 C475 Y10 V12 G13 G15 S237 W242 G244 M248 I265 T338 C341
BS02 NA B G115 V118 G9 V12
BS03 CL B Y142 S371 S407 Y36 S237 S273
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6zpl, PDBe:6zpl, PDBj:6zpl
PDBsum6zpl
PubMed33658720
UniProtP48067|SC6A9_HUMAN Sodium- and chloride-dependent glycine transporter 1 (Gene Name=SLC6A9)

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