Structure of PDB 6zor Chain B

Receptor sequence
>6zorB (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]
MALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMVVPSYDLLLEMLDAH
3D structure
PDB6zor Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist.
ChainB
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QNH B L346 T347 A350 E353 L387 F404 L525 V533 L37 T38 A41 E44 L78 F95 L209 V213
External links
PDB RCSB:6zor, PDBe:6zor, PDBj:6zor
PDBsum6zor
PubMed32910656
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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