Structure of PDB 6znp Chain B

Receptor sequence

>6znpB (length=701) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168)

KKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIKAALSKRGI
DELYTHQYSAFQYVQKGESIVTVTPTASGKTLCYNLPVLQSIAQDETNRA
LYLFPTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGH
IVITNPDMLHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVI
RRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPMRLVDDNGAPSGR
KHFVFYNPPIVNKIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVEIIL
SHIQELVKKEIGTKSIRGYRGGYLPKERREIERGLREGDILGVVSTNALE
LGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRHGESLIIMVANSTPIDQ
YIVRHPEYFFNRSPESARINPENLIILVDHLKCAAYELPFRADEEFGAME
VSDILEYLQEEAVLHRNGERYHWASESFPASNISLRSASQENVVIVDQSD
IANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVD
VEYYTDANLAVQLKIDKTHYGDVTVNALPTIFKKIKMTTFENIGSGPIHL
PSAAWLETLLLLGISNVLQHIVPVYIMCDRNDVHVVSQITIFLYDHYPGG
IGLAEEVFKRFSDINEAAKQLITHCPCHDGCPSCIGTKAKERILQLLDQM
S

3D structure

• PDB: 6znp A skipping rope translocation mechanism in a widespread family of DNA repair helicases.
• Chain: B
• Resolution: 3.16 Å

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	B	T108 K109 Y135 D136 G137 R144 N157 D159 A164 H168 K171 S297 R298 R325 G326 T351 N352 A353 F483 R491 A493 N666	T106 K107 Y133 D134 G135 R142 N155 D157 A162 H166 K169 S292 R293 R320 G321 T346 N347 A348 F478 R486 A488 N631
BS02	ZN	B	C718 C720 C724 C727	C675 C677 C681 C684

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0004386 helicase activity
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0043138 3'-5' DNA helicase activity

Biological Process

• GO:0006289 nucleotide-excision repair
• GO:0032508 DNA duplex unwinding
• GO:0036297 interstrand cross-link repair

External links

• PDB: RCSB:6znp, PDBe:6znp, PDBj:6znp
• PDBsum: 6znp
• PubMed: 33300032
• UniProt: P50830|YPRA_BACSU Uncharacterized ATP-dependent helicase YprA (Gene Name=yprA)