Structure of PDB 6zmd Chain B

Receptor sequence
>6zmdB (length=332) Species: 9606 (Homo sapiens) [Search protein sequence]
GKLEARAALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSE
EDKDIIQADYLYTRALAISPYHEKALVNRDRALPLVEEIDQRYFSIIDSK
VKKVMSIPKGNSALRRVMEETYYHHIYHTVAIGGNTLTLSEIRHILETRY
AVPGKSDEEQNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYV
DPVEAGRFRTTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEF
AALAHYKLVYIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYH
VLCAANEGDVRPFIRFIAKCTETTLDTLLFAT
3D structure
PDB6zmd Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD.
ChainB
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.108: protein adenylyltransferase.
3.1.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QMK B V316 V360 G370 Y400 C404 N407 V215 V259 G269 Y299 C303 N306
External links
PDB RCSB:6zmd, PDBe:6zmd, PDBj:6zmd
PDBsum6zmd
PubMed33893288
UniProtQ9BVA6|FICD_HUMAN Protein adenylyltransferase FICD (Gene Name=FICD)

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