Structure of PDB 6zc7 Chain B

Receptor sequence
>6zc7B (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
MSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGR
IEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKS
3D structure
PDB6zc7 Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
ChainB
Resolution1.48 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 V31 B F259 L260 G261 I262 M282 L319 R320 V323 H324 F17 L18 G19 I20 M40 L77 R78 V81 H82
Gene Ontology
Biological Process
GO:0016055 Wnt signaling pathway

View graph for
Biological Process
External links
PDB RCSB:6zc7, PDBe:6zc7, PDBj:6zc7
PDBsum6zc7
PubMed
UniProtQ92997|DVL3_HUMAN Segment polarity protein dishevelled homolog DVL-3 (Gene Name=DVL3)

[Back to BioLiP]