Structure of PDB 6zc3 Chain B

Receptor sequence
>6zc3B (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
SLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRI
EPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKS
3D structure
PDB6zc3 Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
ChainB
Resolution1.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JOR B F259 L260 G261 I262 L319 R320 V323 H324 F16 L17 G18 I19 L76 R77 V80 H81
Gene Ontology
Biological Process
GO:0016055 Wnt signaling pathway

View graph for
Biological Process
External links
PDB RCSB:6zc3, PDBe:6zc3, PDBj:6zc3
PDBsum6zc3
PubMed
UniProtQ92997|DVL3_HUMAN Segment polarity protein dishevelled homolog DVL-3 (Gene Name=DVL3)

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