Structure of PDB 6z55 Chain B

Receptor sequence
>6z55B (length=357) Species: 9606 (Homo sapiens) [Search protein sequence]
SSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHA
RGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFN
FHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHEN
QLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFD
HEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTH
ENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKEN
CKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTP
EERSFHT
3D structure
PDB6z55 Crystal structure of CLK3 in complex with macrocycle ODS2004070
ChainB
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.12.1: dual-specificity kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PQ5 B V170 A184 K186 F236 L238 L239 L290 D320 V43 A57 K59 F109 L111 L112 L163 D193
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6z55, PDBe:6z55, PDBj:6z55
PDBsum6z55
PubMed
UniProtP49761|CLK3_HUMAN Dual specificity protein kinase CLK3 (Gene Name=CLK3)

[Back to BioLiP]