Structure of PDB 6yyf Chain B

Receptor sequence
>6yyfB (length=152) Species: 9606 (Homo sapiens) [Search protein sequence]
AAVILESIFLKRSQNFKKCLFLLTVHKLSYYEYDFERGRRGSKKGSIDVE
KITCVETVVPEKNPPPERQIPEQISIIERFPYPFQVVYDEGPLYVFSPTE
ELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQIL
EN
3D structure
PDB6yyf Optimising crystallographic systems for structure-guided drug discovery
ChainB
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3IS B K12 S14 Q15 Y39 L111 K11 S13 Q14 Y30 L93
BS02 ZN B H143 C154 C155 C165 H125 C136 C137 C147
Gene Ontology
Biological Process
GO:0035556 intracellular signal transduction

View graph for
Biological Process
External links
PDB RCSB:6yyf, PDBe:6yyf, PDBj:6yyf
PDBsum6yyf
PubMed
UniProtQ06187|BTK_HUMAN Tyrosine-protein kinase BTK (Gene Name=BTK)

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