Structure of PDB 6yx1 Chain B

Receptor sequence
>6yx1B (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQ
YLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLM
VKVVMVTRH
3D structure
PDB6yx1 Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PWT B L678 R679 H735 R736 L28 R29 H85 R86
BS02 THR B V677 L678 H735 R736 V739 V27 L28 H85 R86 V89
BS03 ARG B V677 D706 V27 D56
BS04 LEU B G673 F674 F676 G23 F24 F26
External links
PDB RCSB:6yx1, PDBe:6yx1, PDBj:6yx1
PDBsum6yx1
PubMed34163995
UniProtQ9Y566|SHAN1_HUMAN SH3 and multiple ankyrin repeat domains protein 1 (Gene Name=SHANK1)

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