Structure of PDB 6ymw Chain B

Receptor sequence
>6ymwB (length=340) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SVPIPGIKDISKLKFFYGFKYLWNPTVYNKIFDKLDLTKTYKHPEELKVL
DLYPGVGIQSAIFYNKYCPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRD
PYDWSTYSNLIDEERIFVPEVQSSDHINDKFLTVANVTGEGSEGLIMQWL
SCIGNKNWLYRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTD
TKLIAISDANELKGFDSQCIEEWDPILFSAAEIWPTKGKPIALVEMDPID
FDFDVDNWDYVTRHLMILKRTPLNTVMDSLGHGGQQYFNSRITDKDLLKK
CPIDLTNDEFIYLTKLFMEWPFKPDILMDFVDMYQTEHSG
3D structure
PDB6ymw Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase.
ChainB
Resolution3.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B Y103 D104 W105 E144 G145 M148 Q149 K179 S190 K191 Y102 D103 W104 E143 G144 M147 Q148 K178 S189 K190
BS02 dna B R271 E338 R270 E337
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0034246 mitochondrial transcription factor activity
Biological Process
GO:0006390 mitochondrial transcription
GO:0006391 transcription initiation at mitochondrial promoter
GO:0032259 methylation
GO:0032786 positive regulation of DNA-templated transcription, elongation
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0034245 mitochondrial DNA-directed RNA polymerase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6ymw, PDBe:6ymw, PDBj:6ymw
PDBsum6ymw
PubMed33278362
UniProtP14908|MTF1_YEAST Mitochondrial transcription factor 1 (Gene Name=MTF1)

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