Structure of PDB 6y9b Chain B

Receptor sequence
>6y9bB (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]
LFPQWHLPIKIAAIIASLTFLYTLLREVIHPLATSHQQYFYKIPILVINK
VLPMVSITLLALVYLPGVIAAIVQLHNGTKKFPHWLDKWMLTRKQFGLLS
FFFAVLHAIYSLSYPMRRSYRYKLLNWAYQQVQQNKEDAWIEHDVWRMEI
YVSLGIVGLAILALLAVTSIPSVSDSLTWREFHYIQSKLGIVSLLLGTIH
ALIFAWNKWIDIKQFVWYTPPTFMIAVFLPIVVLIFKSILFLPC
3D structure
PDB6y9b Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1).
ChainB
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM B K116 P119 H175 S179 G223 I224 H268 F272 T290 F291 K50 P53 H107 S111 G155 I156 H200 F204 T222 F223
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0052851 ferric-chelate reductase (NADPH) activity
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0010008 endosome membrane
GO:0016020 membrane

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6y9b, PDBe:6y9b, PDBj:6y9b
PDBsum6y9b
PubMed32409586
UniProtQ9UHE8|STEA1_HUMAN STEAP1 protein (Gene Name=STEAP1)

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