Structure of PDB 6y5n Chain B

Receptor sequence
>6y5nB (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]
KSKNPEDVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRKGVRPELV
GRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKME
FHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYL
PNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGS
NLTGHGYPDASYLDNVLAELTAQGVSE
3D structure
PDB6y5n Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases.
ChainB
Resolution1.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C444 H446 C468 C471 C56 H58 C80 C83
BS02 ZN B C411 C414 H449 C452 C24 C27 H61 C64
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0016567 protein ubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:6y5n, PDBe:6y5n, PDBj:6y5n
PDBsum6y5n
PubMed32948590
UniProtQ86Y01|DTX1_HUMAN E3 ubiquitin-protein ligase DTX1 (Gene Name=DTX1)

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