Structure of PDB 6y48 Chain B

Receptor sequence

>6y48B (length=538) Species: 332952 (Aspergillus flavus NRRL3357)

GNYADELDVDVLIVGAGFGGIYSLYEMRKLGLKAVIYEAGNDIGGTWRWN
CYPGAGVDSEVPEYQLSIPETWKDWTWSTNYPNYEDLRKYFDHVDKVLDI
KKDCAFNSVVVGAHFHTVEGRWHIRTADGRTARAKYFIIAAGFAAKRYIP
EWPGIEKFKGIVHHSSFWPDEKIDVRGKRCAIIGTGASGVQVTQAWGPEA
GELKVFQRTPNLAVPMRKRSLTVEEQEGAKAFYPELFRYREKCFAGFLYT
WCERGVFEDSEEEREQFLEKLWSDGGFRYWVANYKDYLYDAKANRVVYDF
WRKKVRERINDPKDQELLAPSEPPHPWGVKRPCLEYDYYEQFNRPNVDLV
DIKDNSIVDFTEKGIKLQDGTEYEFDVVCIATGFDITTGGMTSMGLHSIH
GDSLKEEWKSGAFTYLGMTVSGYPNMFHLYGPHGPTLLSNGPTTVEIQGR
WIADAIKQMERQGIKYINPTAKAAKEWKAKINELSDKTLFPTTKSTYMGG
SMPGKVFEQVNYAGGEYPYSKEIRAVLPNFNGFDIVKR

3D structure

• PDB: 6y48 Natural Variation in the ‘Control Loop’ of BVMOAFL210 and Its Influence on Regioselectivity and Sulfoxidation
• Chain: B
• Resolution: 2.087 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	B	V31 G32 G34 G36 Y54 E55 A56 G62 T63 W64 W66 Y69 V74 D75 S76 Y81 V127 A157 A158 F160 M411 Y447 N457 G458	V14 G15 G17 G19 Y37 E38 A39 G45 T46 W47 W49 Y52 V57 D58 S59 Y64 V110 A140 A141 F143 M394 Y430 N440 G441
BS02	NAP	B	Y69 D75 F160 P167 T202 G203 A204 S205 Q208 R225 T226 K347 R348 A398 T399 G400 F401 S518	Y52 D58 F143 P150 T185 G186 A187 S188 Q191 R208 T209 K330 R331 A381 T382 G383 F384 S501

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0004497 monooxygenase activity
• GO:0004499 N,N-dimethylaniline monooxygenase activity
• GO:0050660 flavin adenine dinucleotide binding
• GO:0050661 NADP binding

External links

• PDB: RCSB:6y48, PDBe:6y48, PDBj:6y48
• PDBsum: 6y48
• UniProt: A0A7G5K3Z4