Structure of PDB 6xxr Chain B

Receptor sequence
>6xxrB (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
QSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKI
QDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASA
MMHALEVL
3D structure
PDB6xxr Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
ChainB
Resolution1.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y16 W23 K69 N71 F77 Q79 R81 V86 Y13 W20 K66 N68 F74 Q76 R78 V83
External links
PDB RCSB:6xxr, PDBe:6xxr, PDBj:6xxr
PDBsum6xxr
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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