Structure of PDB 6xq7 Chain B

Receptor sequence
>6xq7B (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGG
GPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQ
IPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEK
GVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRA
LRTAPIQPRVWE
3D structure
PDB6xq7 A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 V6V B G56 R57 T58 Q92 G37 R38 T39 Q73
BS02 V6V B V78 L79 P80 V59 L60 P61
BS03 V6V B I91 R179 H180 P181 T183 G184 I72 R160 H161 P162 T164 G165
BS04 V6V B A21 R98 K110 S111 N112 A2 R79 K91 S92 N93
BS05 V6V B R48 L49 Q100 M102 R29 L30 Q81 M83
External links
PDB RCSB:6xq7, PDBe:6xq7, PDBj:6xq7
PDBsum6xq7
PubMed34156100
UniProtQ15109|RAGE_HUMAN Advanced glycosylation end product-specific receptor (Gene Name=AGER)

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