Structure of PDB 6xb8 Chain B

Receptor sequence
>6xb8B (length=200) Species: 648242 (Adeno-associated virus 2 Srivastava/1982) [Search protein sequence]
MPGFYEIVIKVPSDLDEHLPGISDSFVNWVAEKEWELPPDSDMDLNLIEQ
APLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGV
KSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDE
SYIPNYLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQ
3D structure
PDB6xb8 The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B S25 F26 W29 K58 R61 I120 R122 S25 F26 W29 K58 R61 I120 R122
BS02 ZN B E83 H92 E83 H92
External links
PDB RCSB:6xb8, PDBe:6xb8, PDBj:6xb8
PDBsum6xb8
PubMed33270897
UniProtP03132|REP68_AAV2S Protein Rep68 (Gene Name=Rep68)

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