Structure of PDB 6x0k Chain B

Receptor sequence
>6x0kB (length=442) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
LRSTPQDELHDLLCVGFGPASLAIAIALHDALDPRLNKQPKICFLERQKQ
FAWHSGMLVPGSKMQISFIKDLATLRDPRSSFTFLNYLHQKGRLIHFTNL
STFLPARLEFEDYMRWCAQQFSDVVAYGEEVVEVIPGKSDPSSSVVDFFT
VRSRNVETGEISARRTRKVVIAIGGTAKMPSGLPQDPRIIHSSKYCTTLP
ALLKDKSKPYNIAVLGSGQSAAEIFHDLQKRYPNSRTTLIMRDSAMRPSD
DSPFVNEIFNPERVDKFYSQSAAERQRSLLADKATNYSVVRLELIEEIYN
DMYLQRVKNPDETQWQHRILPERKITRVEHHGPQSRMRIHLKSSKPKETL
EVDALMVATGYNRNAHERLLSKVQHLRPTGQDQWKPHRDYRVEMDPSKVS
SEAGIWLQGCNERTHGLSDSLLSVLAVRGGEMVQSIFGEQLE
3D structure
PDB6x0k Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
ChainB
Resolution2.231 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.13.196: L-ornithine N(5)-monooxygenase [NAD(P)H].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FDA B V45 G46 P49 A50 L82 E83 R84 W90 H91 M94 M101 Q102 I103 V168 I210 G211 Y407 S466 L467 L468 V15 G16 P19 A20 L45 E46 R47 W53 H54 M57 M64 Q65 I66 V131 I173 G174 Y361 S420 L421 L422
BS02 ORN B Q102 I103 K107 N293 F296 S469 Q65 I66 K70 N256 F259 S423
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004497 monooxygenase activity
GO:0004499 N,N-dimethylaniline monooxygenase activity
GO:0005506 iron ion binding
GO:0031172 ornithine N5-monooxygenase activity
GO:0070401 NADP+ binding
Biological Process
GO:0006696 ergosterol biosynthetic process
GO:0006879 intracellular iron ion homeostasis
GO:0009058 biosynthetic process
GO:0010106 cellular response to iron ion starvation
GO:0019290 siderophore biosynthetic process
GO:0031169 ferrichrome biosynthetic process
GO:0033214 siderophore-dependent iron import into cell
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0005575 cellular_component

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6x0k, PDBe:6x0k, PDBj:6x0k
PDBsum6x0k
PubMed32723870
UniProtE9QYP0|SIDA_ASPFU L-ornithine N(5)-monooxygenase (Gene Name=sidA)

[Back to BioLiP]