Structure of PDB 6wzx Chain B

Receptor sequence
>6wzxB (length=165) Species: 9606 (Homo sapiens) [Search protein sequence]
GSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTF
FEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEE
LKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYY
HRSSEWYQSLNLTHV
3D structure
PDB6wzx Recognition of nonproline N-terminal residues by the Pro/N-degron pathway.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Q132 K135 L164 E237 G251 A252 S253 Y258 Y273 S277 S278 E279 Q282 Q8 K11 L40 E113 G127 A128 S129 Y134 Y149 S153 S154 E155 Q158
External links
PDB RCSB:6wzx, PDBe:6wzx, PDBj:6wzx
PDBsum6wzx
PubMed32513738
UniProtQ8IVV7|GID4_HUMAN Glucose-induced degradation protein 4 homolog (Gene Name=GID4)

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