Structure of PDB 6wz4 Chain B

Receptor sequence
>6wz4B (length=330) Species: 160488 (Pseudomonas putida KT2440) [Search protein sequence]
KLANVVILATGGTIAGAGASAANSATYQAAKLGVDKLIAGVPELADIANV
RGEQVMQIASESISNDDLLKLGKRVAELAESKDVDGIVITHGTDTLEETA
FFLNLVEKTDKPIVVVGSMRPGTAMSADGMLNLYNAVAVASDKQSRGKGV
LVTMNDEIQSGRDVSMAVNIKTEAFKSAWGPMGMVVEGKSYWFRLPAKRH
TVNSEFDIKQISSLPQVDIAYGYGNVTDTAYKALAQNGAKALIHAGTGNG
SVSSRVVPALQELRKNGVQIIRSSHVNQGGFVLRNAEQPDDKNDWVVAHD
LNPQKARILAMVAMTKTQDSKELQRIFWEY
3D structure
PDB6wz4 Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
ChainB
Resolution1.58 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T20 Y34 T100 D101 M173 E294
Catalytic site (residue number reindexed from 1) T13 Y27 T93 D94 M166 E287
Enzyme Commision number 3.5.1.38: glutamin-(asparagin-)ase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP B T20 Y34 A66 S67 E68 G99 T100 D101 T13 Y27 A59 S60 E61 G92 T93 D94
Gene Ontology
Molecular Function
GO:0004067 asparaginase activity
GO:0004359 glutaminase activity
GO:0016787 hydrolase activity
GO:0050417 glutamin-(asparagin-)ase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006528 asparagine metabolic process
Cellular Component
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:6wz4, PDBe:6wz4, PDBj:6wz4
PDBsum6wz4
PubMed
UniProtQ88K39|ASPQ_PSEPK Glutaminase-asparaginase (Gene Name=ansB)

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