Structure of PDB 6wwq Chain B

Receptor sequence
>6wwqB (length=428) Species: 9823 (Sus scrofa) [Search protein sequence]
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVY
YNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTL
LISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADL
RKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVK
TAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDA
3D structure
PDB6wwq Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP B L246 K252 L246 K252
BS02 GDP B Q11 C12 S138 G141 G142 T143 N204 N226 Q11 C12 S138 G141 G142 T143 N204 N226
BS03 TA1 B V23 D26 H227 F270 P272 T274 G360 V23 D26 H227 F270 P272 T274 G360
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Biological Process
GO:0007017 microtubule-based process
Cellular Component
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wwq, PDBe:6wwq, PDBj:6wwq
PDBsum6wwq
PubMed34131133
UniProtA0A287AZ37

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