Structure of PDB 6ww4 Chain B

Receptor sequence
>6ww4B (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
ARTKQTIHPGVTCDGCQMFPINGSRFKCRNCDDFDFCETCFKTKKHNTRH
TFGRIN
3D structure
PDB6ww4 Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
ChainB
Resolution2.252 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C2708 C2711 C2732 C2735 C13 C16 C37 C40
BS02 ZN B C2723 C2726 H2741 H2745 C28 C31 H46 H50
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6ww4, PDBe:6ww4, PDBj:6ww4
PDBsum6ww4
PubMed32726574
UniProtO95714|HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 (Gene Name=HERC2);
P68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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