Structure of PDB 6wu7 Chain B

Receptor sequence
>6wu7B (length=183) Species: 9606 (Homo sapiens) [Search protein sequence]
QTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKV
PYELIGSMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPR
DLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGELSAEEVSLVCQHVLD
EADGDHDGRLSLEDFQNMILRAPDFLSTFHIRI
3D structure
PDB6wu7 CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
ChainB
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D116 N118 D120 Y122 D127 D112 N114 D116 Y118 D123
BS02 CA B D157 D159 D161 R163 D168 D153 D155 D157 R159 D164
BS03 CA B Q17 D18 T20 Q13 D14 T16
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0055074 calcium ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:6wu7, PDBe:6wu7, PDBj:6wu7
PDBsum6wu7
PubMed34089643
UniProtQ96Q77|CIB3_HUMAN Calcium and integrin-binding family member 3 (Gene Name=CIB3)

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