Structure of PDB 6wnn Chain B

Receptor sequence
>6wnnB (length=416) Species: 1423 (Bacillus subtilis) [Search protein sequence]
DLIEKSKKHLWLPFTQMKDYDENPLIIESGTGIKVKDINGKEYYDGFSSV
WLNVHGHRKKELDDAIKKQLGKIAHSTLLGMTNVPATQLAETLIDISPKK
LTRVFYSDSGAEAMEIALKMAFQYWKNIGKPEKQKFIAMKNGYYKAPIPY
VYRSESGDPDECRDQCLRELAQLLEEHHEEIAALSIESMVQGASGMIVMP
EGYLAGVRELCTTYDVLMIVDEVATGFGRTGKMFACEHENVQPDLMAAGK
GITGGYLPIAVTFATEDIYKAFYDDYENLKTFFHGHSYTGNQLGCAVALE
NLALFESENIVEQVAEKSKKLHFLLQDLHALPHVGDIRQLGFMCGAELVR
SKETKEPYPADRRIGYKVSLKMRELGMLTRPLGDVIAFLPPLASTAEELS
EMVAIMKQAIHEVTSL
3D structure
PDB6wnn Substrate divergence in 7,8-diaminopelargonic acid synthesis: mutagenesis and computational studies of L-lysine dependent Bacillus subtilis BioA
ChainB
Resolution2.59 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F17 Y146 D251 K280
Catalytic site (residue number reindexed from 1) F14 Y143 D221 K250
Enzyme Commision number 2.6.1.105: lysine--8-amino-7-oxononanoate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LLP B H316 S317 H286 S287
BS02 PMP B W54 S112 G113 A114 Y146 E217 D251 K280 W51 S109 G110 A111 Y143 E187 D221 K250
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009102 biotin biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wnn, PDBe:6wnn, PDBj:6wnn
PDBsum6wnn
PubMed
UniProtP53555|BIOK_BACSU L-Lysine--8-amino-7-oxononanoate transaminase (Gene Name=bioK)

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